Benedict Spinoza (1634–1677) is feted as the philosopher par excellence of the popular democratic multitude by Antonio Negri and others. But Spinoza himself expresses a marked ambivalence about the multitude in brief asides, and as for his thoughts on what he calls “the rule of (the) multitude,” that is, democracy, these exist only as meager fragments in his unfinished Tractatus Politicus or Political Treatise. This essay addresses the problem of Spinoza’s multitude. First, I reconstruct a vision of power that is (...) found in the Ethics but that tends to be overlooked in the scholarly literature: power is not just sheer efficacy or imposition of will, but rather involves a capacity for being-affected; I call this the conception of power as sensitivity. The second part of my argument shows how, given Spinoza’s emphatic political naturalism, the conception of power as sensitivity can be extended to his political philosophy to shed light on what Spinoza calls potentia multitudinis, or “the power of the multitude”—a term found solely in the Political Treatise and nowhere else in his oeuvre. This juxtaposition reveals significant qualifications to the liberatory potential of the multitude currently claimed in the scholarly literature. (shrink)

It has often been said that the Zhuangzi 莊子 advocates political abstention, and that its putative skepticism prevents it from contributing in any meaningful way to political thinking: at best the Zhuangzi espouses a sort of anarchism, at worst it is “the night in which all cows are black,” a stance that one scholar has charged is ultimately immoral. This article tracks possible political allusions within the text, and, by reading these against details of social, political, and historical context, sheds (...) light on another strand of the Zhuangzi—one that questions prevailing normative values because it is fiercely critical of scholarly complicity with violent imperial territorial consolidation. (shrink)

The recent ‘material turn’ focuses on materiality in two distinctive ways: one, by including nonhuman agencies, another, by mining indigenous knowledges for alternative conceptions of agency and human–thing relations. A troubling gap persists between the two endeavours. The gap insinuates an us–them dichotomy and, more importantly, curtails communication between radically different visions of thingly agency – thereby impeding the political drive of these conceptual enterprises. This article is an essay in cross-cultural transposition. Through a close reading of a story of (...) a useless tree in an ancient proto-Daoist text, Zhuangzi, the author shows how its fabulist and oneiric form illuminates a distinctive perspective on uselessness. Conversely, the trope of uselessness lets us begin from what she calls a ‘situated affectivity’ amidst more-than-human materialities. The article concludes with a brief comparison of three modalities of uselessness from different ‘cosmologies’ of thought – a foretaste of the potentials of cross-cosmological endeavours. (shrink)

There has recently been a revival of interest in ‘naturalizing’ ethics. A naturalization seeks to vindicate ethical realism — the idea that ethical judgments can be true reflections of a moral reality — without violating the naturalist constraint that science sets the limits of ontology. The recent revival has been prompted by examples of successful scientific reduction (e.g. temperature, water), and by the emergence of new, nonreductive naturalist strategies (e.g. for biological and mental properties). In this paper, I argue against (...) such naturalist approaches to ethics. My argument builds on the traditional one offered by G.E. Moore, namely that a naturalization would fail to respect an existing difference between the meanings of moral and naturalistic terms. I defend this line of argument against the common claim that it cannot block ‘synthetic’ property identities, ones grounded not in meaning equivalences but in empirical discoveries (as in the cases of temperature and water). I then go on to show that the Moorean argument can make trouble even for recent revisionist and nonreductive naturalist approaches. (shrink)

The normative dimension of language and thought has been cited recently in arguments against naturalist reductions of the intentional--of meaning, belief, and desire. These arguments have been met with much scepticism, primarily because their proponents say little about the kind of 'normativity' on which they depend. There is, however, a rich tradition in ethics of thinking about the nature of the normative, and why it might pose a problem for naturalist reduction. ;In this dissertation, I bring the discussions in language (...) and ethics together, arguing that doing so lends clarity and plausibility to the objections to naturalist reduction in both fields. In Part I, I draw from ethics to characterize normativity, and to explain how it provides a barrier to naturalistic reduction. In doing so, I respond to two common criticisms of irreducibility arguments in ethics: that they only show the irreducibility of our concepts of the ethical, not of ethical properties; and that they depend on outdated views of conceptual analysis. I argue that both objections misfire, though for interesting reasons, and that the anti-reduction argument succeeds. ;In Part II I use the characterization of normativity to shed light on recent arguments against reducing the intentional. I examine two prominent authors who have advanced such arguments, Saul Kripke and Donald Davidson. In addition to fleshing out and defending each of their arguments, I develop a general challenge to any reductive approach. The proposal is that intentional items have an essential capacity to define a context of reasons, something to which no naturalist reduction can do justice. ;In Part III I consider a new trend toward non-reductive forms of naturalism. I argue that most current non-reductive accounts also fail to accommodate the requisite normativity. But if the non-reductive, naturalist approach is developed in a certain direction, one which depends on the idea of response-dependency, it can capture just the kind of normativity that is needed. In closing, I briefly defend such an approach to both intentionality and value. (shrink)

The host actin nucleation machinery is subverted by many bacterial pathogens to facilitate their entry, motility, replication, and survival. The majority of research conducted in the past primarily focused on exploitation of a host actin nucleator, the Arp2/3 complex, by bacterial pathogens. Recently, new studies have begun to explore the role of formins, another family of host actin nucleators, in bacterial pathogenesis. This review provides an overview of recent advances in the study of the exploitation of the Arp2/3 complex and (...) formins by bacterial pathogens. Secreted bacterial effector proteins seem to manipulate the regulation of these actin nucleators or functionally mimic them to drive bacterial entry, motility and survival within host cells. An enhanced understanding of how formins are exploited will provide us with greater insight into how a fundamental eurkaryotic cellular process is utilized by bacteria and will also advance our knowledge of host‐pathogen interactions. (shrink)

This exploratory qualitative study investigated how doctoral students reported their personal and professional interaction experiences that they believed might facilitate or impede their academic pursuits in biomedical research. We collected 19 in-depth interviews with doctoral students in biomedical research from eight universities, and we based our qualitative analytic approach on the work of Miles and Huberman. The results indicated that among different sources and types of interaction, academic and emotional interactions from family and teachers in various stages essentially affected students’ (...) persistence in the biomedical science field. In addition, co-mentorship among peers, departmental environment, and volunteer experiences were other essential factors. This study also found related experiences among women and underrepresented minority students that were important to their academic pursuit. (shrink)

In short, the anticipated harm (death) to Ms. A of telling her about her child greatly outweighs the harm she will experience by being lied to. Also, the latter harm can be ameliorated; the former can not.

Background Protecting a person’s right to privacy and confidentiality is important in healthcare services. As future health professionals, nursing students should bear the same responsibility as qualified health professionals in protecting patient privacy. Objectives To investigate nursing students’ practices of patient privacy protection and to identify factors associated with their practices. Research design A cross-sectional study design was adopted. A two-part survey was used to collect two types of data on nursing students: (1) personal characteristics, including demographics, clinical experience and (...) use of information and communication technology and social media and (2) practice of patient privacy protection, collected using the Patient Privacy Scale. Participants and research context: A total of 319 nursing students aged 18 or above, studying pre-registration nursing programmes and who had attended at least one block of clinical placement, were recruited from a university in Hong Kong. Ethical considerations The study received ethical approval from the Survey and Behavioural Research Ethics Committee of the Chinese University of Hong Kong. The participants were informed of the study aim and written consent was obtained before completing the survey. Findings: The mean total score on the Patient Privacy Scale was 119.7 out of 135. Nursing students who were regular users of Instagram and those who had never taken photographs with patients and hence did not need to obtain patient consent were associated with better practices of patient privacy protection (higher total scores on the Patient Privacy Scale). Conclusions The findings improve our understanding of nursing students’ practice of patient privacy protection and the associated factors. This will inform the development and revision of current strategies to enhance nursing students’ practice of patient privacy protection, especially their use of social media. (shrink)

The American idealist movement started in St. Louis, Missouri in 1858, becoming more influential as women joined and influenced its development. Susan Elizabeth Blow was well known as an educator and pedagogical theorist who founded the first public kindergarten program in America (1873-1884). Anna C. Brackett was a feminist and pedagogical theorist and the first female principal of a secondary school (St. Louis Normal School, 1863-72). Grace C. Bibb was a feminist literary critic and the first female dean at the (...) University of Missouri, Columbia (1878-84). American idealism took on a new form in the 1880s with the founding of the Concord School of Philosophy in Massachusetts. Ellen M. Mitchell participated in the movement in both St. Louis and Concord. She was one of the first women to teach philosophy at a co-educational college (University of Denver, 1890-92). Lucia Ames Mead, Marietta Kies, and Eliza Sunderland joined the movement in Concord. Lucia Ames Mead became a chief pacifist theorist in the early twentieth century. Kies and Sunderland were among the first women to earn the Ph.D. in philosophy (University of Michigan, 1891, 1892). Kies wrote on political altruism and shared with Mitchell the distinction of teaching at a coeducational institution (Butler College, 1896-99). These were the first American women as a group to plunge into philosophy proper, bridging those years between the amateur, paraprofessional and professional academic philosopher. Dorothy Rogers's new book at last gives them the attention they deserve. America's First Women Philosophers is indexed in H.W. Wilson's Essay and General Literature Index. (shrink)

Insect molting is elicited by a class of polyhydroxylated steroids, ecdysteroids, that originate in the prothoracic glands. Ecdysteroid synthesis in the prothoracic glands is controlled in large measure by a peptide hormone from the brain, prothoracicotropic hormone (PTTH), which exists in two forms and is released into the general circulation as a result of environmental and developmental cues. The means by which PTTH activates the prothoracic glands has been examined at the cellular level and the data reveal the involvement of (...) cAMP, calcium, calmodulin, cAMP‐dependent protein kinase and the ultimate phosphorylation of a 34 kDa protein tentatively identified as ribosomal protein S6. (shrink)

We describe here recent work on the molecular genetics of mitosis in the filamentous fungus Aspergillus nidulans. Aspergillus is one of three simple eukaryotes with powerful genetic systems that have been used to analyze mitosis. The modern molecular biological techniques available with this organism have made it possible to use mutations to identify genes and proteins that play an important role in mitosis. Three Aspergillus genes that affect mitosis are described. One gene, nimA, is specifically expressed late in the cell (...) cycle and codes for a putative protein kinase that induces mitosis, even in cells blocked in S‐phase. The second gene, bimG, codes for a putative phosphatase that interacts functionally with the nimA kinase. The third gene, bimE, codes for a protein that suppresses mitosis during interphase, apparently by keeping nimA turned off. None of these genes appear to be similar to any of the genes affecting mitosis that have been characterized in other eukaryotes, but rather appear to be elements of a system that prevents mitosis from occurring during interphase. (shrink)

This study is the first examination of the works and lives of the women of the St. Louis philosophical movement and Concord School of Philosophy , two branches of the same idealist movement in America that introduced German thinkers to the American reading public, particularly G. W. F. Hegel. The St. Louis branch of the movement focused primarily on education as a civilizing force in society. The concepts of "self-activity" and self-estrangement were seen as integral to the educative process and (...) therefore became predominant themes of the movement. ;Many of the women in this study were contributors to The Journal of Speculative Philosophy, America's first philosophy journal, edited by William Torrey Harris, the recognized leader of the St. Louis and Concord circles. Figures studied include Susan Elizabeth Blow , kindergarten education theorist; Anna Callender Brackett , proponent of higher education for women; Grace C. Bibb , feminist and educator, Ellen M. Mitchell , feminist and Concord School lecturer; and Marietta Kies , a political theorist who posited altruism as a valid ethical principle for use in public life. A number of less prominent women educators and thinkers of the St. Louis movement and Concord School are also discussed. ;All the women in this study were associates of Harris or his colleagues: Thomas Davidson , John Dewey , George H. Howison , George S. Morris , Denton J. Snider , and Louis Soldan. (shrink)

Community engagement is increasingly emphasized in biomedical research, as a right in itself, and to strengthen ethical practice. We draw on interviews and observations to consider the practical and ethical implications of involving Community Health Workers (CHWs) as part of a community engagement strategy for a vaccine trial on the Kenyan Coast. CHWs were initially engaged as an important network to be informed about the trial. However over time, and in response to community advice, they became involved in trial information (...) sharing and identifying potential participants; thereby taking on roles that overlapped with those of employed fieldworkers (FWs). While CHWs involvement was generally perceived as positive and appreciated, there were challenges in their relations with FWs and other community members, partly related to levels and forms of remuneration. Specifically, payment of CHWs was not as high as for FWs and was based on ‘performance’. This extrinsic motivation had the potential to crowd out CHWs intrinsic motivation to perform their pre-existing community roles. CHWs remuneration potentially also contributed to CHWs distorting trial information to encourage community members to participate; and to researchers encouraging CHWs to utilize their social connections and status to increase the numbers of people who attended information giving sessions. Individual consent processes were protected in this trial through final information sharing and consent being conducted by trained clinical staff who were not embedded in study communities. However, our experiences suggest that roles and remuneration of all front line staff and volunteers involved in trials need careful consideration from the outset, and monitoring and discussion over time. (shrink)

With the rise of naturalism in the art of the late Middle Ages and the Renaissance there developed an extensive and diverse literature about art which helped to explain, justify and shape its new aims. In this book, David Summers provides an investigation of the philosophical and psychological notions invoked in this new theory and criticism. From a thorough examination of the sources, he shows how the medieval language of mental discourse derived from an understanding of classical thought.

Mellor's subject is singular causation between facts, expressed ‘E because C’. His central requirement for causation is that the chance that E if C be greater than the chance that E if C: chc(E)>chc(E). The book is as much about chance as it is about causation. I show that his way of distinguishing chc (E) from the traditional notion of conditional chance leaves than him with a problem about the existence of chQ(P) when Q is false (Section 3); and also (...) that any notion of chance which conforms to the standard calculus has wider application than the causal instances to which Mellor's notion is restricted (Section 8). Other topics discussed may be gleaned from the headings below. 1 Review of D.H. Mellor [1995]: The Facss of Causation, London, Routledge, International Library of Philosophy. (shrink)

The author explores how the discursive practices of social texts relate to the subjectivities of readers. Employing Dorothy Smith's notion of femininity as textually mediated discourse, the author analyzes how teenage girls read the depictions of femininity in the glossy advertisements of fashion magazines. Through interviews with 48 girls aged 13 to 17 years, she explores both why and how young girls negotiate “what it means to be a woman.” Most young girls in her study draw on stereotypical meanings (...) of adult femininity. By giving these stereotypes truth status, these readers valorize not only patriarchal meanings of womanhood but also naturalize associations between femininity and the commodities through which this femininity is expressed as the everyday doing of gender. The author concludes by discussing implications of this study for both a feminist theory and a feminist politics of culture. (shrink)

"Permanent Things reminds us that some of the century's most imaginative minds - G. K. Chesterton, T. S. Eliot, C. S. Lewis, Dorothy Sayers, and Evelyn Waugh - were profoundly at odds with the secularist spirit of the age, seeing progressive enlightenment as ushering in, not a millennium of perfect freedom, but a Waste Land whose inhabitants - Waugh's "vile bodies," Eliot's "hollow men," Lewis's "men without chests" - can find refuge from their boredom and anomie only in the (...) ceaseless acquisition of things or in the consoling illusions of pseudo religions - "distracted from distraction by distraction," as Eliot memorably put it." "How does one explain the desolation of a world which, though richly endowed with material comforts, is mentally and spiritually impoverished? The essayists here are united, as were their subjects, by a need to try to answer this question. Modern man's poverty of spirit, visible alike in so much of his art and architecture, his literature and philosophy and political science, reflects his loss of any good reasons for living - his loss of the Permanent Things." "The Christian writers whose work is eloquently interpreted in this book repay our attention for at least two reasons. First is their ability to sharpen our awareness of what, by any previous civilized standards, must be called the abnormal condition of modern man. For all the writers treated in this book, it was never enough to simply capture the spiritual aridity of modern life. It was also necessary to speak of a moral order that may yet be restored by the expressive power and beauty of the written word."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved. (shrink)